| 1. | During S phase, geminin is a negative regulator of DNA replication.
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| 2. | The encoded protein is a negative regulator of the Wnt signaling pathway.
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| 3. | It is a negative regulator of epithelial cell growth in prostate tissue.
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| 4. | SSI family members are cytokine-inducible negative regulators of cytokine signaling.
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| 5. | RAB23 is an essential negative regulator of the Sonic hedgehog signaling pathway.
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| 6. | LINGO-1 is an essential negative regulator of myelination.
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| 7. | The encoded enzyme is a negative regulator of thiopurine activation and toxicity.
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| 8. | GDF11 is closely related to myostatin, a negative regulator of muscle growth.
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| 9. | This is not surprising because Ets1 is a negative regulator of Th17 cells.
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| 10. | CBL-B functions as a negative regulator of T-cell activation.
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